Daptacel is an important vaccine that protects against Diphtheria, Tetanus, and Pertussis (whooping cough). Like many vaccines, it has the chance to give patients soreness or swelling where the shot was given, fever, irritability, feeling tired, loss of appetite, or vomiting for minor symptoms. Very rarely will more severe reactions occur. However, a question asked about how autism relates to this specific vaccine. The document provided from the FDA does mention autism once on page 11, which is a part of the procedure portion of the document. Due to the common misconception that vaccines cause autism, they were looking for connections between autism and the vaccine. However, no connection between autism and the vaccine were found in any of the clinical trials. In other words the vaccine Daptacel does not cause autism.